H2-mismatched transplantation with repetitive cell infusions and CD40 ligand antibody infusions without myeloablation
نویسندگان
چکیده
منابع مشابه
Adoptive immunotherapy with donor lymphocyte infusions after allogeneic hematopoietic cell transplantation following nonmyeloablative conditioning.
This study retrospectively analyzed data from 446 patients given hematopoietic cell transplants from HLA-matched related or unrelated donors after conditioning with 2 Gy total body irradiation with or without fludarabine and postgrafting immunosuppression with mycophenolate mofetil and cyclosporine following grafting. Fifty-three of 446 patients received donor lymphocyte infusion (DLI) with a m...
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Donor lymphocyte infusions (DLIs) can induce complete and durable remissions in some patients with hematologic malignancies who have relapsed after allogeneic transplantation, providing definitive evidence of a GVL effect. Despite the great promise initially envisioned for DLI as a method to augment GVL after transplantation, it utility is limited by low response rates in diseases other than ch...
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Some of the factors governing the development of edema in the lungs are understood in broad terms. These factors are considered to be no different from those operative in the systemic vessels-increased hydrostatic pressure, decreased oncotic pressure, excessive permeability of the vessels, and decreased lymphatic drainage. Little specific quantitative information is available relative to the pu...
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ژورنال
عنوان ژورنال: British Journal of Haematology
سال: 2002
ISSN: 0007-1048
DOI: 10.1046/j.1365-2141.2002.03801.x